Symposium
CHIRALITY AND CRYSTALLIZATION
Friday 20 June 2008
Radboud University Nijmegen
Kindly sponsored by:
Synthon BV, the Dutch Association for Crystallography, the Dutch Association for
Crystal Growth and the Institute for Molecules and Materials.
Understanding how the single-handedness of biological molecules came about has been of interest to scientists since Pasteur first separated mirror-image crystals of ammonium tartrate. Chirality is important in molecular recognition and as such would seem to be a prerequisite for the origin of life as well as for the efficacy of many pharmaceutical compounds.The number of chiral synthetic drugs, which are administered enantiomerically pure, has increased steadily up to the present value of 80 %. On an industrial scale crystallization is practiced extensively to separate the enantiomers from a racemic mixture. This one-day symposium intends to give an overview of important aspects in the chiral separation of molecules via crystallization up to the latest discovery involving abrasive grinding applied to a racemic solid phase in contact with a racemizing solution leading to an enantiopure solid state with a 100 % yield.
General information
Location: Linnaeus building (room LIN 6) and Huygens building, Faculty of Science, Radboud University, Nijmegen.
Date: 20 June 2008, starting at 10.00 AM.
Registration
To register: send an e-mail with your details (name, address, affiliation, amount due) to: E.Salem AT science.ru.nl (AT meaning @).
You can register up to 16 June 2008.
Please transfer the symposium fee to bank account number 231247834 in the name of 'FNWI' Nijmegen, include your name and the code '6200425' (IBAN: NL02FTSB0231247834 BIC: FTSBNL2R).
Symposium fee is 25 Euro, which includes coffee, lunch and drinks afterwards. Students, NVK and NVKG members pay 15 Euro.
Organizing committee:
Hugo Meekes
Ernst van Eck
René de Gelder
Background image by Loes Modderman
Synthon BV
Nederlandse Vereniging voor Kristallografie
Nederlandse Vereniging voor Kristalgroei
Institute for Molecules and Materials
